Altered cortical network in female with adolescent idiopathic scoliosis

نویسندگان

  • Winnie CW Chu
  • Lin Shi
  • Defeng Wang
  • Jack CY Cheng
چکیده

Objective The aim of the study was to investigate abnormalities in the organization of the brain cortical network in patients with AIS based on MR data. Adolescent idiopathic scoliosis (AIS) is a three dimensional spinal deformity that affects teenagers especially girls between the ages of 10-16 at prevalence of 1-4%. The etiopathogenesis remains uncertain but scientific studies have suggested it is a multifactorial disease included different intrinsic and extrinsic factors. A recent study has demonstrated the abnormal cortical thickness between patients with AIS and healthy controls. Cortical thickness is strongly correlated between regions that are axonally connected. Hence, the hypothesis of altered organization pattern of large-scale structural network in patients with AIS has been tested in this study.

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2015